Effective immunity hinges on the ability to sense infection and cellular transformation. In humans, there is a specialized molecule on the surface of cells termed MR1. MR1 allows sensing of certain small molecule metabolites derived from cellular and microbial sources; however, the breadth of metabolite sensing is unclear. Researchers have identified a form of vitamin B6 bound to MR1 as a means of engaging tumor-reactive immune cells.
Quelle: ScienceDaily | Immunsystem
Titelbild/Grafik: ScienceDaily News
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