What if mRNA vaccines could be made more powerful and less irritating? Scientists at the University of Pennsylvania have found a way to do just that—by tweaking a key molecule in the vaccine’s delivery system. Using a century-old chemical trick called the Mannich reaction, they added anti-inflammatory phenol groups to the lipids that carry mRNA into cells. The result? A new class of lipids that reduce side effects, boost gene-editing success, fight cancer more effectively, and supercharge vaccines like those for COVID-19. This breakthrough could change how we build the next generation of vaccines and therapies.
Quelle: ScienceDaily | Immunsystem
Titelbild/Grafik: ScienceDaily News
Möchten Sie zu diesem Inhalt ein Kommentar abgeben oder haben Sie dazu eine Frage, dann machen Sie dies bitte immer auf der Herausgeberseite!
Weiteres von ScienceDaily | Allergy
- Breakthrough biomaterial heals tissue from the inside out
- First-ever 3D view shows how killer T cells destroy cancer
- Harvard scientists link gut bacteria to depression through hidden inflammation trigger
- A common nutrient could supercharge cancer treatment
- Scientists discover spice synergy that boosts anti-inflammation 100x
- This 5-day diet helped Crohn’s patients feel better fast
- This popular supplement may increase risk of birth defects, study finds
- Your daily coffee may be protecting your brain, 43-year study finds
- DNA origami vaccines could be the next leap beyond mRNA
- Scientists discover the switch that revives exhausted cancer-fighting T cells
